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Cancer-Related Gene Mutation Test

Colorado rates for HCPCS 81311

This service is a genetic laboratory test that looks for specific mutations in a gene that is commonly altered in certain cancers. Results can help guide decisions about cancer treatment, including whether a particular targeted therapy is likely to work. The test is run on a tumor tissue sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test cost?

$380

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $380 for this service. The price depends on where it is billed: about $178 from a physician practice, and about $851 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$178$123 to $380
FacilityA hospital or hospital-owned outpatient department$851$550 to $1,023

How much rates vary

Facilitymedian $851 · 10th to 90th $229 to $1,349Professionalmedian $178 · 10th to 90th $123 to $603
$200$500$1K$2Kfacility $851professional $178

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$616.60
Typical High
$1,380.38
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$223.87
Typical High
$316.23
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$316.23
Median
$891.25
Typical High
$1,348.96
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$660.69
Cigna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$354.81
Typical High
$933.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$151.36
Typical High
$426.58
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$269.15
Typical High
$380.19
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$295.12
Median
$416.87
Typical High
$758.58
Select Health
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$549.54
Typical High
$616.60
Select Health
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$295.12
Typical High
$446.68
United
Setting
Facility
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
United
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$218.78
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$112.20
Median
$112.20
Typical High
$158.49
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$44.67
Median
$44.67
Typical High
$63.10

Where Colorado sits

The same service costs 3.8 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 7th of 51

$380

AK $661AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.