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Heart Transplant Rejection Blood Test

Nationwide rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated July 2026.

Facilitymedian $4,898 · 10th–90th $2,570$13,1830%10%20%10th90th$4,898Professionalmedian $2,630 · 10th–90th $1,349$5,8880%10%20%10th90th$2,630$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$5,248.07
Typical High
$13,803.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,862.09
Median
$2,630.27
Typical High
$6,025.60
BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$4,365.16
Typical High
$13,489.63
BCBS
Setting
Professional
Modifier
Global
Typical Low
$812.83
Median
$1,288.25
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$6,606.93
Typical High
$14,125.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$3,890.45
Typical High
$7,762.47
United
Setting
Facility
Modifier
Global
Typical Low
$1,513.56
Median
$3,235.94
Typical High
$3,890.45
United
Setting
Professional
Modifier
Global
Typical Low
$1,202.26
Median
$1,949.84
Typical High
$4,570.88