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Heart Transplant Rejection Blood Test

Colorado rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated October 2026.

How much does Heart Transplant Rejection Blood Test cost?

$4,266

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $4,266 for this service. The price depends on where it is billed: about $1,950 from a physician practice, and about $9,333 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,950$1,349 to $4,169
FacilityA hospital or hospital-owned outpatient department$9,333$6,026 to $11,220

How much rates vary

Facilitymedian $9,333 · 10th to 90th $2,512 to $14,791Professionalmedian $1,950 · 10th to 90th $1,349 to $6,607
$2K$5K$10K$20Kfacility $9,333professional $1,950

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$3,235.94
Median
$6,760.83
Typical High
$15,135.61
Aetna
Setting
Professional
Modifier
None
Typical Low
$2,454.71
Median
$2,454.71
Typical High
$3,467.37
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$3,388.44
Median
$9,772.37
Typical High
$14,791.08
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1,348.96
Median
$1,348.96
Typical High
$7,079.46
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,905.46
Median
$3,890.45
Typical High
$10,232.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,513.56
Median
$1,737.80
Typical High
$4,677.35
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$2,454.71
Median
$2,951.21
Typical High
$3,548.13
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$3,235.94
Median
$4,570.88
Typical High
$6,760.83
Select Health
Setting
Facility
Modifier
None
Typical Low
$3,235.94
Median
$6,025.60
Typical High
$6,760.83
Select Health
Setting
Professional
Modifier
None
Typical Low
$2,290.87
Median
$3,235.94
Typical High
$4,897.79
United
Setting
Facility
Modifier
None
Typical Low
$3,890.45
Median
$3,890.45
Typical High
$3,890.45
United
Setting
Professional
Modifier
None
Typical Low
$1,202.26
Median
$1,348.96
Typical High
$2,398.83
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,202.26
Median
$1,230.27
Typical High
$1,698.24
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$489.78
Median
$489.78
Typical High
$691.83

Where Colorado sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 4th of 51

$4,266

AK $7,244AL $1,349

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.