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Heart Transplant Rejection Blood Test

South Carolina rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated October 2026.

How much does Heart Transplant Rejection Blood Test cost?

$2,951

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $2,951 for this service. The price depends on where it is billed: about $2,951 from a physician practice, and about $6,761 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,951$2,512 to $3,236
FacilityA hospital or hospital-owned outpatient department$6,761$3,388 to $14,791

How much rates vary

Facilitymedian $6,761 · 10th to 90th $2,512 to $19,953Professionalmedian $2,951 · 10th to 90th $1,549 to $3,890
$2K$5K$10K$20Kfacility $6,761professional $2,951

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$2,511.89
Aetna
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$2,570.40
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$17,378.01
Median
$17,378.01
Typical High
$17,782.79
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$2,951.21
Median
$3,235.94
Typical High
$4,466.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$6,165.95
Median
$8,128.31
Typical High
$19,952.62
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,479.11
Median
$1,778.28
Typical High
$3,890.45
Medcost
Setting
Facility
Modifier
None
Typical Low
$2,511.89
Median
$2,754.23
Typical High
$9,332.54
Medcost
Setting
Professional
Modifier
None
Typical Low
$2,818.38
Median
$2,818.38
Typical High
$4,570.88
United
Setting
Facility
Modifier
None
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$3,890.45
United
Setting
Professional
Modifier
None
Typical Low
$1,348.96
Median
$1,862.09
Typical High
$2,951.21
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,258.93
Median
$1,258.93
Typical High
$1,288.25
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$501.19
Median
$501.19
Typical High
$512.86
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$1,412.54
Median
$1,412.54
Typical High
$2,454.71

Where South Carolina sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 23rd of 51

$2,951

AK $7,244AL $1,349

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.