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Heart Transplant Rejection Blood Test

Missouri rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated October 2026.

How much does Heart Transplant Rejection Blood Test cost?

$2,884

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $2,884 for this service. The price depends on where it is billed: about $2,754 from a physician practice, and about $5,623 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,754$1,288 to $4,677
FacilityA hospital or hospital-owned outpatient department$5,623$3,236 to $10,233

How much rates vary

Facilitymedian $5,623 · 10th to 90th $2,754 to $15,488Professionalmedian $2,754 · 10th to 90th $794 to $8,128
$1K$2K$5K$10K$20Kfacility $5,623professional $2,754

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2,754.23
Median
$4,168.69
Typical High
$6,025.60
Aetna
Setting
Professional
Modifier
None
Typical Low
$2,754.23
Median
$2,818.38
Typical High
$3,715.35
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$14,791.08
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$794.33
Median
$1,584.89
Typical High
$5,888.44
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$6,165.95
Cigna
Setting
Facility
Modifier
None
Typical Low
$2,630.27
Median
$7,244.36
Typical High
$11,748.98
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,479.11
Median
$3,090.30
Typical High
$4,168.69
Medica
Setting
Facility
Modifier
None
Typical Low
$2,454.71
Median
$4,168.69
Typical High
$15,488.17
Medica
Setting
Professional
Modifier
None
Typical Low
$1,621.81
Median
$3,235.94
Typical High
$16,218.10
United
Setting
Facility
Modifier
None
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$2,884.03
United
Setting
Professional
Modifier
None
Typical Low
$1,348.96
Median
$1,949.84
Typical High
$4,265.80
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,380.38
Median
$1,380.38
Typical High
$1,862.09
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$549.54
Median
$562.34
Typical High
$741.31

Where Missouri sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 24th of 51

$2,884

AK $7,244AL $1,349

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.