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Heart Transplant Rejection Blood Test

South Dakota rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated July 2026.

How much does Heart Transplant Rejection Blood Test cost?

$5,129

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $5,129 for this service. The price depends on where it is billed: about $4,266 from a physician practice, and about $6,166 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$4,266$2,512 to $7,586
FacilityA hospital or hospital-owned outpatient department$6,166$6,166 to $6,166

How much rates vary

Facilitymedian $6,166 · 10th to 90th $3,631 to $6,166Professionalmedian $4,266 · 10th to 90th $2,188 to $7,762
$2.0K$5.0K$10.0Kfacility $6,166professional $4,266

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$3,715.35
Typical High
$3,715.35
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,187.76
Median
$2,511.89
Typical High
$3,019.95
Cigna
Setting
Facility
Modifier
Global
Typical Low
$6,165.95
Median
$6,165.95
Typical High
$6,165.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,677.35
Median
$6,165.95
Typical High
$7,762.47
Medica
Setting
Facility
Modifier
Global
Typical Low
$3,090.30
Median
$3,630.78
Typical High
$5,888.44
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,445.44
Median
$1,445.44
Typical High
$16,218.10
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$4,677.35
Median
$7,585.78
Typical High
$8,912.51
United
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,949.84
Typical High
$4,265.80
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$3,235.94

Where South Dakota sits

The same service costs 3.5 times more in Alaska than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $5,129 · 2nd of 51
AK $7,244RI $2,089

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.