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Heart Transplant Rejection Blood Test

Massachusetts rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated July 2026.

How much does Heart Transplant Rejection Blood Test cost?

$3,236

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $3,236 for this service. The price depends on where it is billed: about $3,236 from a physician practice, and about $6,457 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,236$2,291 to $3,236
FacilityA hospital or hospital-owned outpatient department$6,457$3,890 to $8,913

How much rates vary

Facilitymedian $6,457 · 10th to 90th $2,399 to $10,233Professionalmedian $3,236 · 10th to 90th $1,950 to $7,943
$100.0$1.0K$10.0Kfacility $6,457professional $3,236

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,995.26
Median
$5,623.41
Typical High
$10,471.29
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$2,089.30
Typical High
$9,772.37
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$3,715.35
Typical High
$10,471.29
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$1,698.24
Median
$3,235.94
Typical High
$10,715.19
BCBS
Setting
Facility
Modifier
Global
Typical Low
$5,128.61
Median
$6,456.54
Typical High
$10,232.93
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3,019.95
Median
$3,019.95
Typical High
$3,019.95
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,089.30
Median
$2,511.89
Typical High
$6,309.57
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,778.28
Median
$3,467.37
Typical High
$8,511.38
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$2,454.71
Median
$4,677.35
Typical High
$5,495.41
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$5,370.32
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$3,715.35
Typical High
$10,471.29
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$1,698.24
Median
$3,235.94
Typical High
$10,715.19
United
Setting
Facility
Modifier
Global
Typical Low
$1,949.84
Median
$3,235.94
Typical High
$3,715.35
United
Setting
Professional
Modifier
Global
Typical Low
$1,698.24
Median
$3,235.94
Typical High
$6,165.95

Where Massachusetts sits

The same service costs 3.5 times more in Alaska than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $3,236 · 20th of 51
AK $7,244RI $2,089

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.