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Heart Transplant Rejection Blood Test

Massachusetts rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated October 2026.

How much does Heart Transplant Rejection Blood Test cost?

$3,236

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $3,236 for this service. The price depends on where it is billed: about $3,236 from a physician practice, and about $4,677 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,236$1,950 to $8,128
FacilityA hospital or hospital-owned outpatient department$4,677$3,388 to $6,607

How much rates vary

Facilitymedian $4,677 · 10th to 90th $2,399 to $9,550Professionalmedian $3,236 · 10th to 90th $1,698 to $16,218
$100$200$500$1K$2K$5K$10Kfacility $4,677professional $3,236

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$1,995.26
Median
$3,981.07
Typical High
$8,912.51
Aetna
Setting
Professional
Modifier
None
Typical Low
$1,995.26
Median
$1,995.26
Typical High
$1,995.26
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$2,398.83
Median
$3,715.35
Typical High
$10,000.00
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$1,698.24
Median
$6,165.95
Typical High
$16,218.10
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$3,801.89
Median
$6,456.54
Typical High
$11,481.54
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$3,019.95
Median
$3,019.95
Typical High
$3,019.95
Cigna
Setting
Facility
Modifier
None
Typical Low
$2,089.30
Median
$2,511.89
Typical High
$6,309.57
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,949.84
Median
$3,388.44
Typical High
$12,589.25
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$4,677.35
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$4,677.35
Median
$4,677.35
Typical High
$5,495.41
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$1,698.24
Median
$3,235.94
Typical High
$7,244.36
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$2,398.83
Median
$3,715.35
Typical High
$10,000.00
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$1,698.24
Median
$6,165.95
Typical High
$16,218.10
United
Setting
Facility
Modifier
None
Typical Low
$2,884.03
Median
$3,235.94
Typical High
$3,890.45
United
Setting
Professional
Modifier
None
Typical Low
$1,288.25
Median
$1,949.84
Typical High
$6,165.95
Well Sense
Setting
Facility
Modifier
None
Typical Low
$2,884.03
Median
$3,981.07
Typical High
$5,888.44
Well Sense
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,000.00
Median
$1,000.00
Typical High
$1,000.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$398.11
Median
$398.11
Typical High
$398.11
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$3,235.94
Median
$4,168.69
Typical High
$5,011.87

Where Massachusetts sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 19th of 51

$3,236

AK $7,244AL $1,349

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.