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Heart Transplant Rejection Blood Test

Minnesota rates for HCPCS 81595

A blood test for people living with a transplanted heart that measures how active a set of genes is in immune cells and turns the pattern into a score showing how likely the body is to be rejecting the organ. A reassuring score can spare the patient a biopsy of the heart muscle, which requires threading a catheter into the heart. It is used for routine monitoring rather than for diagnosing a rejection episode already underway.

Rates data updated October 2026.

How much does Heart Transplant Rejection Blood Test cost?

$3,236

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $3,236 for this service. The price depends on where it is billed: about $3,236 from a physician practice, and about $3,236 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,236$2,818 to $3,890
FacilityA hospital or hospital-owned outpatient department$3,236$3,020 to $7,943

How much rates vary

Facilitymedian $3,236 · 10th to 90th $3,020 to $12,303Professionalmedian $3,236 · 10th to 90th $1,778 to $6,310
$2K$5K$10K$20Kfacility $3,236professional $3,236

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$3,019.95
Median
$3,019.95
Typical High
$3,019.95
Aetna
Setting
Professional
Modifier
None
Typical Low
$3,019.95
Median
$3,019.95
Typical High
$3,548.13
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$3,090.30
Median
$3,235.94
Typical High
$7,943.28
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$2,570.40
Median
$2,884.03
Typical High
$3,235.94
Cigna
Setting
Facility
Modifier
None
Typical Low
$6,456.54
Median
$10,471.29
Typical High
$30,199.52
Cigna
Setting
Professional
Modifier
None
Typical Low
$3,801.89
Median
$4,265.80
Typical High
$6,309.57
Health Partners
Setting
Facility
Modifier
None
Typical Low
$6,165.95
Median
$10,000.00
Typical High
$23,988.33
Health Partners
Setting
Professional
Modifier
None
Typical Low
$3,715.35
Median
$3,715.35
Typical High
$6,025.60
Medica
Setting
Facility
Modifier
None
Typical Low
$3,890.45
Median
$5,128.61
Typical High
$6,456.54
Medica
Setting
Professional
Modifier
None
Typical Low
$1,445.44
Median
$3,235.94
Typical High
$16,218.10
United
Setting
Facility
Modifier
None
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$3,890.45
United
Setting
Professional
Modifier
None
Typical Low
$1,348.96
Median
$2,570.40
Typical High
$7,585.78
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$1,513.56
Median
$1,513.56
Typical High
$1,513.56
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$602.56
Median
$602.56
Typical High
$602.56
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,513.56
Median
$1,513.56
Typical High
$1,778.28
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$602.56
Median
$602.56
Typical High
$707.95

Where Minnesota sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 18th of 51

$3,236

AK $7,244AL $1,349

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.