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Tissue-Matching (HLA) Genetic Blood Test

Nationwide rates for HCPCS 81377

A genetic blood test that identifies specific tissue-matching markers on white blood cells, known as HLA type. It is most often used to check how well a potential donor's tissue matches a recipient's before an organ or bone marrow transplant, since a closer match lowers the risk of rejection. It may also be used in certain disease-risk or family-relationship testing.

Rates data updated July 2026.

Facilitymedian $155 · 10th–90th $79$4270%10%10th90th$155Professionalmedian $83 · 10th–90th $52$1910%20%10th90th$83$0.1$1.0$10.0$100.0$1.0K$10.0K$100.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$77.62
Median
$154.88
Typical High
$398.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$81.28
Typical High
$173.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$95.50
Median
$138.04
Typical High
$436.52
BCBS
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$61.66
Typical High
$186.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$199.53
Typical High
$436.52
Cigna
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$114.82
Typical High
$229.09
United
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$95.50
Typical High
$125.89
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$56.23
Typical High
$151.36