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Tissue-Matching (HLA) Genetic Blood Test

Virginia rates for HCPCS 81377

A genetic blood test that identifies specific tissue-matching markers on white blood cells, known as HLA type. It is most often used to check how well a potential donor's tissue matches a recipient's before an organ or bone marrow transplant, since a closer match lowers the risk of rejection. It may also be used in certain disease-risk or family-relationship testing.

Rates data updated October 2026.

How much does Tissue-Matching (HLA) Genetic Blood Test cost?

$87.10

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $87.10 for this service. The price depends on where it is billed: about $75.86 from a physician practice, and about $141 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$75.86$56.23 to $95.50
FacilityA hospital or hospital-owned outpatient department$141$95.50 to $229

How much rates vary

Facilitymedian $141 · 10th to 90th $95 to $490Professionalmedian $76 · 10th to 90th $46 to $162
$50$200$1K$5Kfacility $141professional $76

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$70.79
Median
$87.10
Typical High
$239.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$70.79
Typical High
$87.10
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$95.50
Typical High
$467.74
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$56.23
Typical High
$83.18
CareFirst
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$85.11
Typical High
$100.00
Cigna
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$186.21
Typical High
$323.59
Cigna
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$70.79
Typical High
$181.97
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$104.71
Typical High
$131.83
Medcost
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$181.97
Medcost
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$125.89
Typical High
$281.84
Sentara
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$154.88
Typical High
$10,232.93
Sentara
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$134.90
Typical High
$7,413.10
United
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$114.82
United
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$56.23
Typical High
$144.54
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$35.48
Median
$35.48
Typical High
$43.65
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$14.13
Median
$14.13
Typical High
$17.38

Where Virginia sits

The same service costs 3.5 times more in Kansas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 35th of 51

$87.10

KS $224AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.