go back

Tissue-Matching (HLA) Genetic Blood Test

South Dakota rates for HCPCS 81377

A genetic blood test that identifies specific tissue-matching markers on white blood cells, known as HLA type. It is most often used to check how well a potential donor's tissue matches a recipient's before an organ or bone marrow transplant, since a closer match lowers the risk of rejection. It may also be used in certain disease-risk or family-relationship testing.

Rates data updated July 2026.

How much does Tissue-Matching (HLA) Genetic Blood Test cost?

$100

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $100 for this service. The price depends on where it is billed: about $100 from a physician practice, and about $182 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$100$89.13 to $186
FacilityA hospital or hospital-owned outpatient department$182$174 to $182

How much rates vary

Facilitymedian $182 · 10th to 90th $107 to $182Professionalmedian $100 · 10th to 90th $63 to $229
$50$100$200facility $182professional $100

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$107.15
Typical High
$107.15
Aetna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$95.50
Typical High
$100.00
Cigna
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
Cigna
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$181.97
Typical High
$229.09
Medica
Setting
Facility
Modifier
Global
Typical Low
$89.13
Median
$107.15
Typical High
$346.74
Medica
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$64.57
Typical High
$478.63
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$229.09
Typical High
$263.03
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$64.57
Typical High
$125.89
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$95.50
Typical High
$95.50

Where South Dakota sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 14th of 51

$100

AK $214DC $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.