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Tissue-Matching (HLA) Genetic Blood Test

North Carolina rates for HCPCS 81377

A genetic blood test that identifies specific tissue-matching markers on white blood cells, known as HLA type. It is most often used to check how well a potential donor's tissue matches a recipient's before an organ or bone marrow transplant, since a closer match lowers the risk of rejection. It may also be used in certain disease-risk or family-relationship testing.

Rates data updated October 2026.

How much does Tissue-Matching (HLA) Genetic Blood Test cost?

$126

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $126 for this service. The price depends on where it is billed: about $126 from a physician practice, and about $209 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$126$85.11 to $269
FacilityA hospital or hospital-owned outpatient department$209$75.86 to $380

How much rates vary

Facilitymedian $209 · 10th to 90th $76 to $427Professionalmedian $126 · 10th to 90th $47 to $501
$50$100$200$500facility $209professional $126

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$75.86
Typical High
$208.93
Aetna
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$75.86
Typical High
$114.82
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$380.19
Typical High
$380.19
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$151.36
Typical High
$501.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$208.93
Typical High
$426.58
Cigna
Setting
Professional
Modifier
None
Typical Low
$43.65
Median
$85.11
Typical High
$138.04
Medcost
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$75.86
Typical High
$112.20
Medcost
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$125.89
Typical High
$190.55
United
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$63.10
Typical High
$125.89
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$38.02
Median
$38.02
Typical High
$56.23
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$15.14
Median
$15.14
Typical High
$22.91
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$63.10
Median
$63.10
Typical High
$128.82

Where North Carolina sits

The same service costs 3.5 times more in Kansas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 9th of 51

$126

KS $224AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.