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Tissue-Matching (HLA) Genetic Blood Test

Colorado rates for HCPCS 81377

A genetic blood test that identifies specific tissue-matching markers on white blood cells, known as HLA type. It is most often used to check how well a potential donor's tissue matches a recipient's before an organ or bone marrow transplant, since a closer match lowers the risk of rejection. It may also be used in certain disease-risk or family-relationship testing.

Rates data updated July 2026.

How much does Tissue-Matching (HLA) Genetic Blood Test cost?

$102

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $102 for this service. The price depends on where it is billed: about $72.44 from a physician practice, and about $234 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$72.44$60.26 to $75.86
FacilityA hospital or hospital-owned outpatient department$234$126 to $398

How much rates vary

Facilitymedian $234 · 10th to 90th $72 to $479Professionalmedian $72 · 10th to 90th $40 to $102
$50$100$200$500facility $234professional $72

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$208.93
Typical High
$446.68
Aetna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$72.44
Typical High
$102.33
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$117.49
Median
$281.84
Typical High
$478.63
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$39.81
Typical High
$95.50
Cigna
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$61.66
Typical High
$251.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$52.48
Typical High
$138.04
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$72.44
Median
$95.50
Typical High
$144.54
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$134.90
Typical High
$436.52
Select Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$173.78
Typical High
$199.53
Select Health
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$95.50
Typical High
$141.25
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$95.50
Typical High
$141.25
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$52.48
Typical High
$64.57

Where Colorado sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 13th of 51

$102

AK $214DC $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.