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Tissue-Matching (HLA) Genetic Blood Test

South Carolina rates for HCPCS 81377

A genetic blood test that identifies specific tissue-matching markers on white blood cells, known as HLA type. It is most often used to check how well a potential donor's tissue matches a recipient's before an organ or bone marrow transplant, since a closer match lowers the risk of rejection. It may also be used in certain disease-risk or family-relationship testing.

Rates data updated July 2026.

How much does Tissue-Matching (HLA) Genetic Blood Test cost?

$77.62

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $77.62 for this service. The price depends on where it is billed: about $75.86 from a physician practice, and about $138 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$75.86$74.13 to $83.18
FacilityA hospital or hospital-owned outpatient department$138$95.50 to $234

How much rates vary

Facilitymedian $138 · 10th to 90th $74 to $331Professionalmedian $76 · 10th to 90th $63 to $110
$50$100$200$500facility $138professional $76

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$151.36
Typical High
$331.13
Aetna
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$85.11
BCBS
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$630.96
Typical High
$676.08
BCBS
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$109.65
Typical High
$199.53
Cigna
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$281.84
Typical High
$537.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$58.88
Typical High
$100.00
Medcost
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$91.20
Typical High
$186.21
United
Setting
Facility
Modifier
Global
Typical Low
$85.11
Median
$95.50
Typical High
$114.82
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$63.10
Typical High
$125.89

Where South Carolina sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 48th of 51

$77.62

AK $214DC $70.79

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.