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Tumor Signaling Pathway Activity Score

Nationwide rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated June 2026.

Facilitymedian $5,012 · 10th–90th $2,570$14,4540%10%10th90th$5,012Professionalmedian $2,570 · 10th–90th $1,698$3,9810%20%10th90th$2,570$5.0$20.0$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,691.53
Median
$5,623.41
Typical High
$14,791.08
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,570.40
Typical High
$3,388.44
BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,454.71
Median
$5,011.87
Typical High
$15,488.17
BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,148.15
Median
$1,348.96
Typical High
$4,168.69
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$6,309.57
Typical High
$14,125.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,715.35
Median
$4,677.35
Typical High
$8,709.64
United
Setting
Facility
Modifier
Global
Typical Low
$1,513.56
Median
$3,235.94
Typical High
$3,801.89
United
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,905.46
Typical High
$3,801.89