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Tumor Signaling Pathway Activity Score

South Dakota rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated July 2026.

How much does Tumor Signaling Pathway Activity Score cost?

$5,495

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $5,495 for this service. Most negotiated rates run $3,020 to $7,586.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $3,631 · 10th to 90th $2,239 to $5,129Professionalmedian $6,166 · 10th to 90th $2,138 to $8,318
$2K$5K$10Kfacility $3,631professional $6,166

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$3,630.78
Typical High
$3,630.78
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,137.96
Median
$2,511.89
Typical High
$3,019.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$6,165.95
Typical High
$7,585.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$3,019.95
Median
$3,090.30
Typical High
$5,888.44
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,621.81
Median
$1,621.81
Typical High
$15,848.93
Midlands
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$7,413.10
Typical High
$8,709.64
United
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,905.46
Typical High
$4,265.80
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$3,235.94

Where South Dakota sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 2nd of 51

$5,495

AK $7,244WY $1,905

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.