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Tumor Signaling Pathway Activity Score

Maryland rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated July 2026.

How much does Tumor Signaling Pathway Activity Score cost?

$2,399

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $2,399 for this service. Most negotiated rates run $1,995 to $2,630.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $1,349 · 10th to 90th $1,349 to $2,455Professionalmedian $2,399 · 10th to 90th $1,413 to $2,884
$2K$5Kfacility $1,349professional $2,399

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,398.83
Typical High
$2,691.53
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$2,884.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,698.24
Median
$1,698.24
Typical High
$1,698.24
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,715.35
Typical High
$4,786.30
United
Setting
Facility
Modifier
Global
Typical Low
$1,348.96
Median
$1,348.96
Typical High
$2,454.71
United
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,445.44
Typical High
$2,818.38
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$1,584.89
Median
$1,584.89
Typical High
$1,584.89

Where Maryland sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 42nd of 51

$2,399

AK $7,244WY $1,905

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.