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Tumor Signaling Pathway Activity Score

California rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated July 2026.

How much does Tumor Signaling Pathway Activity Score cost?

$2,692

Typical negotiated rate. In California, July 2026.

Insurers have agreed to pay about $2,692 for this service. The price depends on where it is billed: about $2,455 from a physician practice, and about $7,413 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,455$1,660 to $3,090
FacilityA hospital or hospital-owned outpatient department$7,413$4,786 to $13,804

How much rates vary

Facilitymedian $7,413 · 10th to 90th $2,754 to $17,783Professionalmedian $2,455 · 10th to 90th $1,148 to $5,888
$100$500$2K$10Kfacility $7,413professional $2,455

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,548.13
Median
$7,413.10
Typical High
$18,197.01
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,570.40
Typical High
$3,019.95
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$9,332.54
Median
$9,332.54
Typical High
$16,218.10
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,148.15
Median
$1,659.59
Typical High
$6,606.93
Blue Shield
Setting
Facility
Modifier
Global
Typical Low
$1,949.84
Median
$6,606.93
Typical High
$9,332.54
Blue Shield
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$3,981.07
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$4,786.30
Typical High
$10,715.19
Contra Costa Health
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,548.13
Typical High
$4,365.16
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$3,548.13
Typical High
$5,623.41
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$15,135.61
Median
$15,135.61
Typical High
$15,135.61
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$15,848.93
Median
$23,988.33
Typical High
$23,988.33
Providence
Setting
Facility
Modifier
Global
Typical Low
$2,137.96
Median
$3,801.89
Typical High
$7,244.36
Providence
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,548.13
Typical High
$4,786.30
United
Setting
Facility
Modifier
Global
Typical Low
$1,348.96
Median
$3,235.94
Typical High
$3,801.89
United
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,348.96
Typical High
$6,606.93

Where California sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

California· 27th of 51

$2,692

AK $7,244WY $1,905

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.