go back

Tumor Signaling Pathway Activity Score

Massachusetts rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated July 2026.

How much does Tumor Signaling Pathway Activity Score cost?

$3,236

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $3,236 for this service. The price depends on where it is billed: about $3,236 from a physician practice, and about $6,026 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,236$2,399 to $3,236
FacilityA hospital or hospital-owned outpatient department$6,026$4,365 to $9,333

How much rates vary

Facilitymedian $6,026 · 10th to 90th $2,239 to $10,471Professionalmedian $3,236 · 10th to 90th $1,905 to $5,129
$2K$5K$10Kfacility $6,026professional $3,236

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$7,244.36
Typical High
$10,471.29
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,238.72
Typical High
$2,570.40
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$3,548.13
Median
$8,511.38
Typical High
$15,135.61
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$3,235.94
Typical High
$10,715.19
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$2,511.89
Typical High
$5,128.61
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,890.45
Median
$3,890.45
Typical High
$4,897.79
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$5,370.32
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$4,570.88
Typical High
$5,370.32
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$5,128.61
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$3,548.13
Median
$8,511.38
Typical High
$15,135.61
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$3,235.94
Typical High
$10,715.19
United
Setting
Facility
Modifier
Global
Typical Low
$1,905.46
Median
$3,235.94
Typical High
$3,801.89
United
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$3,235.94
Typical High
$5,623.41

Where Massachusetts sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 16th of 51

$3,236

AK $7,244WY $1,905

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.