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Tumor Signaling Pathway Activity Score

Pennsylvania rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated July 2026.

How much does Tumor Signaling Pathway Activity Score cost?

$2,692

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $2,692 for this service. The price depends on where it is billed: about $2,570 from a physician practice, and about $6,166 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,570$1,905 to $2,692
FacilityA hospital or hospital-owned outpatient department$6,166$3,890 to $7,943

How much rates vary

Facilitymedian $6,166 · 10th to 90th $2,692 to $11,482Professionalmedian $2,570 · 10th to 90th $1,738 to $3,236
$2K$5K$10Kfacility $6,166professional $2,570

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,691.53
Median
$6,165.95
Typical High
$11,481.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,570.40
Typical High
$3,019.95
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$2,511.89
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$4,365.16
Typical High
$10,964.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$15,488.17
Median
$15,488.17
Typical High
$15,488.17
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$4,168.69
Typical High
$4,570.88
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$3,235.94
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$5,370.32
Typical High
$8,128.31
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$3,801.89
Median
$6,760.83
Typical High
$11,481.54
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,570.40
Typical High
$9,332.54
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$3,235.94
Median
$7,943.28
Typical High
$7,943.28
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$3,235.94
Median
$3,235.94
Typical High
$3,235.94
United
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$3,235.94
Typical High
$3,801.89
United
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,905.46
Typical High
$4,265.80

Where Pennsylvania sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 30th of 51

$2,692

AK $7,244WY $1,905

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.