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Tumor Signaling Pathway Activity Score

Nebraska rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated July 2026.

How much does Tumor Signaling Pathway Activity Score cost?

$2,089

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $2,089 for this service. The price depends on where it is billed: about $2,089 from a physician practice, and about $3,020 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,089$1,905 to $5,012
FacilityA hospital or hospital-owned outpatient department$3,020$1,148 to $8,128

How much rates vary

Facilitymedian $3,020 · 10th to 90th $282 to $8,511Professionalmedian $2,089 · 10th to 90th $1,905 to $7,586
$500$1K$2K$5K$10Kfacility $3,020professional $2,089

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$8,511.38
Typical High
$15,848.93
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$7,585.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$295.12
Typical High
$575.44
BCBS
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$5,011.87
Typical High
$5,248.07
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$6,165.95
Typical High
$7,585.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$1,905.46
Median
$3,981.07
Typical High
$15,135.61
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,905.46
Typical High
$9,332.54
Midlands
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
United
Setting
Facility
Modifier
Global
Typical Low
$1,348.96
Median
$3,019.95
Typical High
$3,235.94
United
Setting
Professional
Modifier
Global
Typical Low
$1,819.70
Median
$1,905.46
Typical High
$8,912.51

Where Nebraska sits

The same service costs 3.8 times more in Alaska than in Wyoming. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 48th of 51

$2,089

AK $7,244WY $1,905

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.