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Tumor Signaling Pathway Activity Score

Nebraska rates for HCPCS 0262U

Measures how active seven cell-signaling pathways are inside a solid tumor — estrogen receptor, androgen receptor, PI3K, MAPK, Hedgehog, TGF-beta and Notch — and reports each as an index value. Gene activity is read from a preserved (paraffin-embedded) piece of the tumor.

Rates data updated June 2026.

Facilitymedian $6,457 · 10th–90th $295$15,8490%10%10th90th$6,457Professionalmedian $2,089 · 10th–90th $1,905$5,2480%20%10th90th$2,089$500.0$1.0K$2.0K$5.0K$10.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$6,456.54
Median
$8,511.38
Typical High
$15,848.93
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$2,454.71
BCBS
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$295.12
Typical High
$575.44
BCBS
Setting
Professional
Modifier
Global
Typical Low
$4,570.88
Median
$5,011.87
Typical High
$5,248.07
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$6,165.95
Typical High
$7,585.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$1,905.46
Median
$3,981.07
Typical High
$15,135.61
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,905.46
Typical High
$9,332.54
Midlands
Setting
Professional
Modifier
Global
Typical Low
$3,801.89
Median
$3,801.89
Typical High
$3,801.89
United
Setting
Facility
Modifier
Global
Typical Low
$1,148.15
Median
$1,905.46
Typical High
$6,456.54
United
Setting
Professional
Modifier
Global
Typical Low
$1,819.70
Median
$1,905.46
Typical High
$6,456.54