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IFNL3 (IL28B) Gene Variant Test

Nationwide rates for HCPCS 81283

Tests a blood sample for variations in the IFNL3 gene, also known as IL28B. The pattern a person carries affects how their immune system handles hepatitis C infection and how likely they are to respond to certain antiviral treatments. The result is used to help choose and plan treatment.

Rates data updated July 2026.

Facilitymedian $110 · 10th–90th $60$3240%10%20%10th90th$110Professionalmedian $62 · 10th–90th $35$1410%10%20%10th90th$62$0.1$1.0$10.0$100.0$1.0K$10.0K$100.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$58.88
Median
$117.49
Typical High
$316.23
Aetna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$60.26
Typical High
$138.04
BCBS
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$97.72
Typical High
$331.13
BCBS
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$41.69
Typical High
$141.25
Cigna
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$147.91
Typical High
$323.59
Cigna
Setting
Professional
Modifier
Global
Typical Low
$34.67
Median
$85.11
Typical High
$173.78
United
Setting
Facility
Modifier
Global
Typical Low
$34.67
Median
$74.13
Typical High
$87.10
United
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$43.65
Typical High
$100.00