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IFNL3 (IL28B) Gene Variant Test

Iowa rates for HCPCS 81283

Tests a blood sample for variations in the IFNL3 gene, also known as IL28B. The pattern a person carries affects how their immune system handles hepatitis C infection and how likely they are to respond to certain antiviral treatments. The result is used to help choose and plan treatment.

Rates data updated July 2026.

Facilitymedian $112 · 10th–90th $56$2140%10%20%10th90th$112Professionalmedian $65 · 10th–90th $46$4900%10%10th90th$65$10.0$20.0$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$151.36
Typical High
$213.80
Aetna
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$64.57
Typical High
$489.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$147.91
Typical High
$147.91
Cigna
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$141.25
Typical High
$173.78
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$109.65
Typical High
$131.83
Medica
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$87.10
Typical High
$186.21
Medica
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$87.10
Typical High
$295.12
Midlands
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$97.72
Typical High
$97.72
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$79.43
Typical High
$154.88
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$162.18
United
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$45.71
Typical High
$186.21
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$74.13