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IFNL3 (IL28B) Gene Variant Test

Pennsylvania rates for HCPCS 81283

Tests a blood sample for variations in the IFNL3 gene, also known as IL28B. The pattern a person carries affects how their immune system handles hepatitis C infection and how likely they are to respond to certain antiviral treatments. The result is used to help choose and plan treatment.

Rates data updated July 2026.

Facilitymedian $145 · 10th–90th $62$2750%10%10th90th$145Professionalmedian $59 · 10th–90th $41$1620%20%40%10th90th$59$50.0$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$61.66
Median
$144.54
Typical High
$263.03
Aetna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$58.88
Typical High
$263.03
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$371.54
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$57.54
Typical High
$57.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$120.23
Typical High
$251.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$34.67
Median
$64.57
Typical High
$131.83
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$95.50
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$74.13
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$85.11
Typical High
$141.25
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$58.88
Median
$144.54
Typical High
$263.03
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$58.88
Typical High
$263.03
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$83.18
Typical High
$181.97
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$83.18
United
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$74.13
Typical High
$87.10
United
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$43.65
Typical High
$102.33