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IFNL3 (IL28B) Gene Variant Test

Massachusetts rates for HCPCS 81283

Tests a blood sample for variations in the IFNL3 gene, also known as IL28B. The pattern a person carries affects how their immune system handles hepatitis C infection and how likely they are to respond to certain antiviral treatments. The result is used to help choose and plan treatment.

Rates data updated July 2026.

Facilitymedian $151 · 10th–90th $56$2400%10%10th90th$151Professionalmedian $74 · 10th–90th $46$1820%20%40%10th90th$74$50.0$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$125.89
Typical High
$213.80
Aetna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$56.23
Typical High
$218.78
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$85.11
Typical High
$239.88
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$74.13
Typical High
$245.47
BCBS
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$151.36
Typical High
$213.80
BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
Cigna
Setting
Facility
Modifier
Global
Typical Low
$48.98
Median
$58.88
Typical High
$147.91
Cigna
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$89.13
Typical High
$151.36
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$436.52
Typical High
$7,079.46
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$107.15
Typical High
$125.89
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$134.90
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$85.11
Typical High
$239.88
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$74.13
Typical High
$245.47
United
Setting
Facility
Modifier
Global
Typical Low
$45.71
Median
$74.13
Typical High
$91.20
United
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$74.13
Typical High
$165.96