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IFNL3 (IL28B) Gene Variant Test

Colorado rates for HCPCS 81283

Tests a blood sample for variations in the IFNL3 gene, also known as IL28B. The pattern a person carries affects how their immune system handles hepatitis C infection and how likely they are to respond to certain antiviral treatments. The result is used to help choose and plan treatment.

Rates data updated July 2026.

Facilitymedian $178 · 10th–90th $56$3720%5%10%10th90th$178Professionalmedian $56 · 10th–90th $31$780%20%10th90th$56$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$162.18
Typical High
$346.74
Aetna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$56.23
Typical High
$77.62
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$218.78
Typical High
$371.54
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$30.90
Typical High
$74.13
Cigna
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$47.86
Typical High
$194.98
Cigna
Setting
Professional
Modifier
Global
Typical Low
$33.88
Median
$38.90
Typical High
$107.15
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$74.13
Typical High
$109.65
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$102.33
Median
$104.71
Typical High
$151.36
Select Health
Setting
Facility
Modifier
Global
Typical Low
$77.62
Median
$134.90
Typical High
$154.88
Select Health
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$74.13
Typical High
$109.65
United
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$74.13
Typical High
$109.65
United
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$31.62
Typical High
$53.70