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IFNL3 (IL28B) Gene Variant Test

Minnesota rates for HCPCS 81283

Tests a blood sample for variations in the IFNL3 gene, also known as IL28B. The pattern a person carries affects how their immune system handles hepatitis C infection and how likely they are to respond to certain antiviral treatments. The result is used to help choose and plan treatment.

Rates data updated July 2026.

Facilitymedian $186 · 10th–90th $74$5370%10%20%10th90th$186Professionalmedian $74 · 10th–90th $59$1070%20%40%10th90th$74$10.0$20.0$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
Aetna
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$69.18
Typical High
$218.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$134.90
BCBS
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$74.13
Typical High
$74.13
Cigna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$251.19
Typical High
$691.83
Cigna
Setting
Professional
Modifier
Global
Typical Low
$85.11
Median
$107.15
Typical High
$151.36
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$162.18
Median
$234.42
Typical High
$537.03
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$85.11
Median
$85.11
Typical High
$141.25
Medica
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$128.82
Typical High
$223.87
Medica
Setting
Professional
Modifier
Global
Typical Low
$31.62
Median
$45.71
Typical High
$194.98
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$85.11
Typical High
$87.10
United
Setting
Professional
Modifier
Global
Typical Low
$37.15
Median
$74.13
Typical High
$158.49