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Genetic Test For Hereditary Iron Overload (HFE Gene)

Nationwide rates for HCPCS 81256

A blood sample is tested for the most common genetic changes linked to hereditary hemochromatosis, a condition in which the body absorbs and stores too much iron over time. Identifying these gene changes can help confirm a diagnosis in someone with signs of iron overload or a family history of the condition.

Rates data updated July 2026.

Facilitymedian $123 · 10th–90th $58$3800%10%10th90th$123Professionalmedian $66 · 10th–90th $39$1410%20%10th90th$66$0.1$1.0$10.0$100.0$1.0K$10.0K$100.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$128.82
Typical High
$407.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$63.10
Typical High
$138.04
BCBS
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$97.72
Typical High
$295.12
BCBS
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$42.66
Typical High
$134.90
Cigna
Setting
Facility
Modifier
Global
Typical Low
$57.54
Median
$138.04
Typical High
$302.00
Cigna
Setting
Professional
Modifier
Global
Typical Low
$34.67
Median
$77.62
Typical High
$158.49
United
Setting
Facility
Modifier
Global
Typical Low
$37.15
Median
$66.07
Typical High
$97.72
United
Setting
Professional
Modifier
Global
Typical Low
$27.54
Median
$44.67
Typical High
$134.90