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Genetic Test For Hereditary Iron Overload (HFE Gene)

Minnesota rates for HCPCS 81256

A blood sample is tested for the most common genetic changes linked to hereditary hemochromatosis, a condition in which the body absorbs and stores too much iron over time. Identifying these gene changes can help confirm a diagnosis in someone with signs of iron overload or a family history of the condition.

Rates data updated October 2026.

How much does Genetic Test For Hereditary Iron Overload (HFE Gene) cost?

$75.86

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $66.07 from a physician practice, and about $166 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$56.23 to $83.18
FacilityA hospital or hospital-owned outpatient department$166$61.66 to $457

How much rates vary

Facilitymedian $166 · 10th to 90th $48 to $525Professionalmedian $66 · 10th to 90th $46 to $135
$50$100$200$500facility $166professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$47.86
Median
$79.43
Typical High
$524.81
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$61.66
Typical High
$77.62
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$66.07
Typical High
$346.74
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$58.88
Typical High
$66.07
Cigna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$208.93
Typical High
$616.60
Cigna
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$85.11
Typical High
$125.89
Health Partners
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$199.53
Typical High
$478.63
Health Partners
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$75.86
Typical High
$125.89
Medica
Setting
Facility
Modifier
None
Typical Low
$77.62
Median
$158.49
Typical High
$446.68
Medica
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$77.62
Typical High
$323.59
United
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$77.62
United
Setting
Professional
Modifier
None
Typical Low
$27.54
Median
$53.70
Typical High
$154.88
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$30.90
Median
$30.90
Typical High
$30.90
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$12.30
Median
$12.30
Typical High
$12.30
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$30.90
Median
$30.90
Typical High
$33.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$12.30
Median
$12.30
Typical High
$13.18

Where Minnesota sits

The same service costs 4.8 times more in Kansas than in Illinois. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 19th of 51

$75.86

KS $240IL $50.12

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.