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Genetic Test For Hereditary Iron Overload (HFE Gene)

Massachusetts rates for HCPCS 81256

A blood sample is tested for the most common genetic changes linked to hereditary hemochromatosis, a condition in which the body absorbs and stores too much iron over time. Identifying these gene changes can help confirm a diagnosis in someone with signs of iron overload or a family history of the condition.

Rates data updated July 2026.

How much does Genetic Test For Hereditary Iron Overload (HFE Gene) cost?

$66.07

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $66.07 for this service. The price depends on where it is billed: about $66.07 from a physician practice, and about $162 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$66.07$66.07 to $77.62
FacilityA hospital or hospital-owned outpatient department$162$105 to $229

How much rates vary

Facilitymedian $162 · 10th to 90th $66 to $407Professionalmedian $66 · 10th to 90th $54 to $166
$50$100$200$500$1K$2Kfacility $162professional $66

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$66.07
Median
$186.21
Typical High
$512.86
Aetna
Setting
Professional
Modifier
Global
Typical Low
$52.48
Median
$67.61
Typical High
$194.98
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$91.20
Typical High
$223.87
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$67.61
Typical High
$218.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$162.18
Typical High
$229.09
BCBS
Setting
Professional
Modifier
Global
Typical Low
$83.18
Median
$83.18
Typical High
$83.18
Cigna
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$89.13
Typical High
$138.04
Cigna
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$69.18
Typical High
$169.82
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$93.33
Typical High
$112.20
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$125.89
Health New England
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$123.03
Typical High
$186.21
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$91.20
Typical High
$223.87
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$67.61
Typical High
$218.78
United
Setting
Facility
Modifier
Global
Typical Low
$53.70
Median
$66.07
Typical High
$107.15
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$66.07
Typical High
$154.88

Where Massachusetts sits

The same service costs 3.6 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 33rd of 51

$66.07

NE $178DC $48.98

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.