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Genetic Test For Hereditary Iron Overload (HFE Gene)

Colorado rates for HCPCS 81256

A blood sample is tested for the most common genetic changes linked to hereditary hemochromatosis, a condition in which the body absorbs and stores too much iron over time. Identifying these gene changes can help confirm a diagnosis in someone with signs of iron overload or a family history of the condition.

Rates data updated October 2026.

How much does Genetic Test For Hereditary Iron Overload (HFE Gene) cost?

$87.10

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $87.10 for this service. The price depends on where it is billed: about $40.74 from a physician practice, and about $191 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$40.74$27.54 to $85.11
FacilityA hospital or hospital-owned outpatient department$191$117 to $229

How much rates vary

Facilitymedian $191 · 10th to 90th $50 to $302Professionalmedian $41 · 10th to 90th $28 to $135
$50$100$200$500facility $191professional $41

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$114.82
Typical High
$302.00
Aetna
Setting
Professional
Modifier
None
Typical Low
$48.98
Median
$50.12
Typical High
$91.20
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$194.98
Typical High
$302.00
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$27.54
Median
$27.54
Typical High
$144.54
Cigna
Setting
Facility
Modifier
None
Typical Low
$38.02
Median
$79.43
Typical High
$204.17
Cigna
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$40.74
Typical High
$95.50
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$63.10
Typical High
$109.65
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$93.33
Typical High
$165.96
Select Health
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$120.23
Typical High
$138.04
Select Health
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$66.07
Typical High
$97.72
United
Setting
Facility
Modifier
None
Typical Low
$77.62
Median
$77.62
Typical High
$77.62
United
Setting
Professional
Modifier
None
Typical Low
$27.54
Median
$37.15
Typical High
$47.86
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$24.55
Median
$25.12
Typical High
$34.67
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$9.77
Median
$10.00
Typical High
$13.80

Where Colorado sits

The same service costs 4.8 times more in Kansas than in Illinois. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 13th of 51

$87.10

KS $240IL $50.12

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.