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Genetic Test For Hereditary Iron Overload (HFE Gene)

South Carolina rates for HCPCS 81256

A blood sample is tested for the most common genetic changes linked to hereditary hemochromatosis, a condition in which the body absorbs and stores too much iron over time. Identifying these gene changes can help confirm a diagnosis in someone with signs of iron overload or a family history of the condition.

Rates data updated July 2026.

How much does Genetic Test For Hereditary Iron Overload (HFE Gene) cost?

$91.20

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $91.20 for this service. The price depends on where it is billed: about $53.70 from a physician practice, and about $372 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$53.70$51.29 to $72.44
FacilityA hospital or hospital-owned outpatient department$372$162 to $525

How much rates vary

Facilitymedian $372 · 10th to 90th $63 to $631Professionalmedian $54 · 10th to 90th $50 to $162
$50$100$200$500facility $372professional $54

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$389.05
Typical High
$630.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$52.48
Typical High
$91.20
BCBS
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$123.03
Typical High
$446.68
BCBS
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$181.97
Typical High
$363.08
Cigna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$194.98
Typical High
$371.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$30.20
Median
$41.69
Typical High
$69.18
Medcost
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$64.57
Typical High
$134.90
United
Setting
Facility
Modifier
Global
Typical Low
$58.88
Median
$66.07
Typical High
$77.62
United
Setting
Professional
Modifier
Global
Typical Low
$27.54
Median
$44.67
Typical High
$89.13

Where South Carolina sits

The same service costs 3.6 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 10th of 51

$91.20

NE $178DC $48.98

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.