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Genetic Test For Hereditary Iron Overload (HFE Gene)

South Dakota rates for HCPCS 81256

A blood sample is tested for the most common genetic changes linked to hereditary hemochromatosis, a condition in which the body absorbs and stores too much iron over time. Identifying these gene changes can help confirm a diagnosis in someone with signs of iron overload or a family history of the condition.

Rates data updated October 2026.

How much does Genetic Test For Hereditary Iron Overload (HFE Gene) cost?

$75.86

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $75.86 from a physician practice, and about $74.13 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$75.86$58.88 to $135
FacilityA hospital or hospital-owned outpatient department$74.13$74.13 to $126

How much rates vary

Facilitymedian $74 · 10th to 90th $63 to $126Professionalmedian $76 · 10th to 90th $44 to $158
$50$100$200$500facility $74professional $76

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$45.71
Median
$45.71
Typical High
$74.13
Aetna
Setting
Professional
Modifier
None
Typical Low
$43.65
Median
$43.65
Typical High
$61.66
Cigna
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$125.89
Typical High
$125.89
Cigna
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$125.89
Typical High
$158.49
Medica
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$74.13
Typical High
$120.23
Medica
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$58.88
Typical High
$134.90
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$151.36
Typical High
$177.83
United
Setting
Professional
Modifier
None
Typical Low
$27.54
Median
$45.71
Typical High
$89.13
Wellmark
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07

Where South Dakota sits

The same service costs 4.8 times more in Kansas than in Illinois. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 20th of 51

$75.86

KS $240IL $50.12

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.