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Oral Fluid Drug And Interaction Test

Nationwide rates for HCPCS 0116U

Checks a saliva (oral fluid) sample for 35 medications and drugs as part of monitoring a person's treatment. Alongside the drug findings it reports a rating of the risk that the medications involved could interact with one another.

Rates data updated June 2026.

Facilitymedian $372 · 10th–90th $195$1,1220%20%10th90th$372Professionalmedian $195 · 10th–90th $129$2950%50%10th90th$195$0.0$0.2$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$426.58
Typical High
$1,122.02
Aetna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$194.98
Typical High
$275.42
BCBS
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$331.13
Typical High
$1,122.02
BCBS
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$48.98
Typical High
$281.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$478.63
Typical High
$1,071.52
Cigna
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$363.08
Typical High
$588.84
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$245.47
Typical High
$295.12
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$141.25
Typical High
$281.84