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Oral Fluid Drug And Interaction Test

Florida rates for HCPCS 0116U

Checks a saliva (oral fluid) sample for 35 medications and drugs as part of monitoring a person's treatment. Alongside the drug findings it reports a rating of the risk that the medications involved could interact with one another.

Rates data updated July 2026.

How much does Oral Fluid Drug And Interaction Test cost?

$174

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $162 from a physician practice, and about $457 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$162$148 to $174
FacilityA hospital or hospital-owned outpatient department$457$224 to $708

How much rates vary

Facilitymedian $457 · 10th to 90th $178 to $1,230Professionalmedian $162 · 10th to 90th $148 to $200
$100$200$500$1Kfacility $457professional $162

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$676.08
Typical High
$1,348.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$162.18
Typical High
$190.55
AvMed
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$245.47
AvMed
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$245.47
Typical High
$245.47
Cigna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$208.93
Typical High
$1,000.00
Cigna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$281.84
Typical High
$380.19
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$457.09
Median
$457.09
Typical High
$457.09
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$147.91
Typical High
$223.87
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$223.87
Typical High
$245.47
United
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$104.71
Typical High
$245.47
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$147.91
Typical High
$245.47

Where Florida sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 48th of 51

$174

SD $479CT $162

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.