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Oral Fluid Drug And Interaction Test

Iowa rates for HCPCS 0116U

Checks a saliva (oral fluid) sample for 35 medications and drugs as part of monitoring a person's treatment. Alongside the drug findings it reports a rating of the risk that the medications involved could interact with one another.

Rates data updated July 2026.

How much does Oral Fluid Drug And Interaction Test cost?

$245

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $191 from a physician practice, and about $389 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$191$162 to $295
FacilityA hospital or hospital-owned outpatient department$389$245 to $646

How much rates vary

Facilitymedian $389 · 10th to 90th $191 to $708Professionalmedian $191 · 10th to 90th $148 to $537
$100$200$500$1Kfacility $389professional $191

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$588.84
Typical High
$707.95
Aetna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$190.55
Typical High
$190.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$707.95
Median
$707.95
Typical High
$707.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$478.63
Typical High
$588.84
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$309.03
Typical High
$446.68
Medica
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$295.12
Typical High
$691.83
Medica
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$147.91
Typical High
$562.34
Midlands
Setting
Professional
Modifier
Global
Typical Low
$302.00
Median
$302.00
Typical High
$302.00
Midlands
Setting
Facility
Modifier
Global
Typical Low
$707.95
Median
$707.95
Typical High
$707.95
United
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$549.54
United
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$147.91
Typical High
$537.03
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$245.47
Typical High
$245.47

Where Iowa sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 19th of 51

$245

SD $479CT $162

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.