go back

Oral Fluid Drug And Interaction Test

Missouri rates for HCPCS 0116U

Checks a saliva (oral fluid) sample for 35 medications and drugs as part of monitoring a person's treatment. Alongside the drug findings it reports a rating of the risk that the medications involved could interact with one another.

Rates data updated July 2026.

How much does Oral Fluid Drug And Interaction Test cost?

$245

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $214 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$214$123 to $282
FacilityA hospital or hospital-owned outpatient department$324$245 to $427

How much rates vary

Facilitymedian $324 · 10th to 90th $240 to $575Professionalmedian $214 · 10th to 90th $46 to $417
$50$100$200$500$1Kfacility $324professional $214

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$416.87
Typical High
$575.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$239.88
Typical High
$416.87
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$870.96
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$147.91
Typical High
$389.05
Cigna
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$524.81
Typical High
$1,258.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$354.81
Medica
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$426.58
Typical High
$1,174.90
Medica
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$147.91
Typical High
$269.15
United
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$245.47
Typical High
$295.12
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$147.91
Typical High
$295.12

Where Missouri sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 17th of 51

$245

SD $479CT $162

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.