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Oral Fluid Drug And Interaction Test

Pennsylvania rates for HCPCS 0116U

Checks a saliva (oral fluid) sample for 35 medications and drugs as part of monitoring a person's treatment. Alongside the drug findings it reports a rating of the risk that the medications involved could interact with one another.

Rates data updated July 2026.

How much does Oral Fluid Drug And Interaction Test cost?

$209

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $209 for this service. The price depends on where it is billed: about $200 from a physician practice, and about $417 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$200$191 to $209
FacilityA hospital or hospital-owned outpatient department$417$288 to $676

How much rates vary

Facilitymedian $417 · 10th to 90th $209 to $933Professionalmedian $200 · 10th to 90th $132 to $245
$100$200$500$1Kfacility $417professional $200

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$512.86
Typical High
$933.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$199.53
Typical High
$234.42
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$8,511.38
Typical High
$77,624.71
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$371.54
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$354.81
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$144.54
Typical High
$354.81
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$245.47
Typical High
$245.47
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$229.09
Typical High
$426.58
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$588.84
Typical High
$870.96
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$199.53
Typical High
$724.44
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$269.15
Typical High
$616.60
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$245.47
Typical High
$269.15
United
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$245.47
Typical High
$295.12
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$147.91
Typical High
$371.54

Where Pennsylvania sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 25th of 51

$209

SD $479CT $162

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.