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Oral Fluid Drug And Interaction Test

North Carolina rates for HCPCS 0116U

Checks a saliva (oral fluid) sample for 35 medications and drugs as part of monitoring a person's treatment. Alongside the drug findings it reports a rating of the risk that the medications involved could interact with one another.

Rates data updated July 2026.

How much does Oral Fluid Drug And Interaction Test cost?

$200

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $200 from a physician practice, and about $288 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$200$178 to $200
FacilityA hospital or hospital-owned outpatient department$288$200 to $776

How much rates vary

Facilitymedian $288 · 10th to 90th $182 to $1,122Professionalmedian $200 · 10th to 90th $148 to $245
$100$200$500$1Kfacility $288professional $200

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$426.58
Typical High
$812.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$199.53
Typical High
$199.53
BCBS
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$741.31
Typical High
$776.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$223.87
Typical High
$223.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$537.03
Typical High
$1,122.02
Cigna
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$302.00
Typical High
$380.19
Medcost
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$199.53
Typical High
$245.47
Medcost
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$162.18
Typical High
$186.21
United
Setting
Facility
Modifier
Global
Typical Low
$109.65
Median
$245.47
Typical High
$295.12
United
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$123.03
Typical High
$245.47
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$1,174.90

Where North Carolina sits

The same service costs 3.0 times more in South Dakota than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 36th of 51

$200

SD $479CT $162

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.