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Hepatitis B Immune Globulin Injection

Nationwide rates for HCPCS 90371 · Hyperhep B, Nabi-HB

An injection into a muscle of ready-made antibodies against hepatitis B, giving immediate protection after a possible exposure. It is used for newborns of infected mothers, after a needlestick, and after sexual contact with an infected person. Protection begins within hours but wears off after a few months, so it is normally paired with vaccination.

Rates data updated July 2026.

How much does Hepatitis B Immune Globulin Injection cost?

$145

Typical negotiated rate. Nationwide, July 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $174 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 64 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$141 to $174
FacilityA hospital or hospital-owned outpatient department$174$141 to $282

How much rates vary

Facilitymedian $174 · 10th to 90th $141 to $447Professionalmedian $141 · 10th to 90th $138 to $209
$1.0$10.0$100.0$1.0K$10.0K$100.0Kfacility $174professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$346.74
Aetna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$239.88
BCBS
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$186.21
Typical High
$389.05
BCBS
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$141.25
Typical High
$204.17
Cigna
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$263.03
Typical High
$489.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$177.83
Typical High
$181.97
United
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$275.42
United
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$162.18
Typical High
$199.53

What it costs in each state

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

AK $209AL $141

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.