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Hepatitis B Immune Globulin Injection

South Dakota rates for HCPCS 90371 · Hyperhep B, Nabi-HB

An injection into a muscle of ready-made antibodies against hepatitis B, giving immediate protection after a possible exposure. It is used for newborns of infected mothers, after a needlestick, and after sexual contact with an infected person. Protection begins within hours but wears off after a few months, so it is normally paired with vaccination.

Rates data updated July 2026.

How much does Hepatitis B Immune Globulin Injection cost?

$141

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $141 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $141 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$141 to $158
FacilityA hospital or hospital-owned outpatient department$141$141 to $141

How much rates vary

Facilitymedian $141 · 10th to 90th $120 to $141Professionalmedian $141 · 10th to 90th $141 to $178
$200facility $141professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$141.25
Typical High
$141.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$169.82
Cigna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$177.83
Medica
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$190.55
Typical High
$354.81
Medica
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$144.54
Typical High
$158.49
Midlands
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$154.88
Typical High
$154.88
United
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$151.36
Typical High
$194.98
Wellmark
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$141.25
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$141.25

Where South Dakota sits

Rates are fairly even across states for this service. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 35th of 51

$141

AK $209AL $141

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.