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Hepatitis B Immune Globulin Injection

Illinois rates for HCPCS 90371 · Hyperhep B, Nabi-HB

An injection into a muscle of ready-made antibodies against hepatitis B, giving immediate protection after a possible exposure. It is used for newborns of infected mothers, after a needlestick, and after sexual contact with an infected person. Protection begins within hours but wears off after a few months, so it is normally paired with vaccination.

Rates data updated October 2026.

How much does Hepatitis B Immune Globulin Injection cost?

$191

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $191 for this service. The price depends on where it is billed: about $182 from a physician practice, and about $372 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$182$158 to $200
FacilityA hospital or hospital-owned outpatient department$372$282 to $525

How much rates vary

Facilitymedian $372 · 10th to 90th $155 to $933Professionalmedian $182 · 10th to 90th $138 to $282
$200$500$1Kfacility $372professional $182

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$549.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$138.04
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$512.86
Typical High
$1,230.27
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$190.55
Typical High
$199.53
Cigna
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$371.54
Typical High
$436.52
Cigna
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
Hally Health
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$190.55
Typical High
$426.58
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
United
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$309.03
United
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$169.82
Typical High
$199.53
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$27.54
Typical High
$27.54
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$20.42
Median
$20.42
Typical High
$20.42
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$13.80
Median
$13.80
Typical High
$13.80

Where Illinois sits

The same service costs 1.8 times more in Arizona than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 5th of 51

$191

AZ $245RI $138

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.