go back

Hepatitis B Immune Globulin Injection

Massachusetts rates for HCPCS 90371 · Hyperhep B, Nabi-HB

An injection into a muscle of ready-made antibodies against hepatitis B, giving immediate protection after a possible exposure. It is used for newborns of infected mothers, after a needlestick, and after sexual contact with an infected person. Protection begins within hours but wears off after a few months, so it is normally paired with vaccination.

Rates data updated October 2026.

How much does Hepatitis B Immune Globulin Injection cost?

$178

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $178 for this service. The price depends on where it is billed: about $162 from a physician practice, and about $191 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$162$138 to $200
FacilityA hospital or hospital-owned outpatient department$191$151 to $282

How much rates vary

Facilitymedian $191 · 10th to 90th $138 to $398Professionalmedian $162 · 10th to 90th $138 to $214
$100$200$500facility $191professional $162

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$269.15
Aetna
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$138.04
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$389.05
Typical High
$457.09
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$162.18
Typical High
$213.80
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$154.88
Typical High
$281.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$218.78
Median
$331.13
Typical High
$794.33
Cigna
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$208.93
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$181.97
Typical High
$204.17
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$158.49
Typical High
$218.78
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$389.05
Typical High
$457.09
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$162.18
Typical High
$213.80
United
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$138.04
United
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$199.53
Typical High
$213.80
Well Sense
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$194.98
Typical High
$316.23
Well Sense
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$165.96
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$27.54
Typical High
$27.54
Aetna
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$20.42
Median
$20.42
Typical High
$20.42
Aetna
Setting
Professional
Modifier
56 · Pre-op care only
Typical Low
$13.80
Median
$13.80
Typical High
$13.80

Where Massachusetts sits

The same service costs 1.8 times more in Arizona than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 16th of 51

$178

AZ $245RI $138

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.