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General-Purpose Immunoassay Lab Test

South Dakota rates for HCPCS 83516

A laboratory test that uses an antibody-based method to detect and measure a specific substance in a sample, applied when there is no more specific, dedicated test already established for that particular substance. It is a general-purpose test format applied to a wide range of possible substances rather than one single, named analyte.

Rates data updated July 2026.

How much does General-Purpose Immunoassay Lab Test cost?

$45.71

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $45.71 for this service. The price depends on where it is billed: about $31.62 from a physician practice, and about $58.88 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$31.62$10.47 to $54.95
FacilityA hospital or hospital-owned outpatient department$58.88$43.65 to $61.66

How much rates vary

Facilitymedian $59 · 10th to 90th $22 to $78Professionalmedian $32 · 10th to 90th $9 to $65
$5.0$10.0$20.0$50.0$100.0$200.0facility $59professional $32

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$60.26
Typical High
$77.62
Aetna
Setting
Professional
Modifier
Global
Typical Low
$8.91
Median
$45.71
Typical High
$100.00
Avera
Setting
Facility
Modifier
Global
Typical Low
$10.47
Median
$11.75
Typical High
$17.38
Avera
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$11.75
Typical High
$12.02
Cigna
Setting
Facility
Modifier
Global
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$21.88
Typical High
$27.54
Medica
Setting
Facility
Modifier
Global
Typical Low
$10.96
Median
$18.62
Typical High
$97.72
Medica
Setting
Professional
Modifier
Global
Typical Low
$6.92
Median
$8.13
Typical High
$16.22
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$17.38
Median
$27.54
Typical High
$31.62
United
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$13.80
Typical High
$13.80
United
Setting
Professional
Modifier
Global
Typical Low
$4.79
Median
$10.47
Typical High
$16.22
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$11.48
Typical High
$11.48

Where South Dakota sits

The same service costs 4.5 times more in South Dakota than in Nevada. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $45.71 · 1st of 51
SD $45.71NV $10.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.