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General-Purpose Immunoassay Lab Test

Maryland rates for HCPCS 83516

A laboratory test that uses an antibody-based method to detect and measure a specific substance in a sample, applied when there is no more specific, dedicated test already established for that particular substance. It is a general-purpose test format applied to a wide range of possible substances rather than one single, named analyte.

Rates data updated October 2026.

How much does General-Purpose Immunoassay Lab Test cost?

$8.71

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $8.71 for this service. Most negotiated rates run $7.59 to $9.55.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $11 · 10th to 90th $8 to $15Professionalmedian $9 · 10th to 90th $6 to $13
$5$10$20facility $11professional $9

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$8.51
Median
$11.75
Typical High
$16.98
Aetna
Setting
Professional
Modifier
None
Typical Low
$6.31
Median
$8.51
Typical High
$11.22
CareFirst
Setting
Professional
Modifier
None
Typical Low
$8.32
Median
$9.12
Typical High
$10.47
Cigna
Setting
Facility
Modifier
None
Typical Low
$6.17
Median
$8.13
Typical High
$14.79
Cigna
Setting
Professional
Modifier
None
Typical Low
$6.17
Median
$11.48
Typical High
$28.18
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$11.48
Median
$13.18
Typical High
$22.39
United
Setting
Professional
Modifier
None
Typical Low
$5.25
Median
$6.61
Typical High
$10.00
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$11.22
Median
$11.22
Typical High
$11.22
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$4.27
Median
$4.37
Typical High
$4.37
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$1.70
Median
$1.74
Typical High
$1.74

Where Maryland sits

The same service costs 5.2 times more in Minnesota than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 51st of 51

$8.71

MN $45.71MD $8.71

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.