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General-Purpose Immunoassay Lab Test

Maryland rates for HCPCS 83516

A laboratory test that uses an antibody-based method to detect and measure a specific substance in a sample, applied when there is no more specific, dedicated test already established for that particular substance. It is a general-purpose test format applied to a wide range of possible substances rather than one single, named analyte.

Rates data updated July 2026.

How much does General-Purpose Immunoassay Lab Test cost?

$11.22

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $11.22 for this service. The price depends on where it is billed: about $10.23 from a physician practice, and about $66.07 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$10.23$8.71 to $11.75
FacilityA hospital or hospital-owned outpatient department$66.07$48.98 to $81.28

How much rates vary

Facilitymedian $66 · 10th to 90th $9 to $91Professionalmedian $10 · 10th to 90th $8 to $14
$5.0$10.0$20.0$50.0$100.0facility $66professional $10

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$8.51
Median
$66.07
Typical High
$91.20
Aetna
Setting
Professional
Modifier
Global
Typical Low
$8.51
Median
$10.23
Typical High
$14.13
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$3.80
Median
$9.12
Typical High
$11.22
Cigna
Setting
Facility
Modifier
Global
Typical Low
$6.17
Median
$7.94
Typical High
$14.79
Cigna
Setting
Professional
Modifier
Global
Typical Low
$6.61
Median
$11.48
Typical High
$28.18
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$13.80
Typical High
$22.39
United
Setting
Facility
Modifier
Global
Typical Low
$4.79
Median
$5.50
Typical High
$12.59
United
Setting
Professional
Modifier
Global
Typical Low
$5.25
Median
$6.76
Typical High
$12.59
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$5.75
Median
$11.22
Typical High
$11.22

Where Maryland sits

The same service costs 4.5 times more in South Dakota than in Nevada. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Maryland $11.22 · 45th of 51
SD $45.71NV $10.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.