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General-Purpose Immunoassay Lab Test

South Carolina rates for HCPCS 83516

A laboratory test that uses an antibody-based method to detect and measure a specific substance in a sample, applied when there is no more specific, dedicated test already established for that particular substance. It is a general-purpose test format applied to a wide range of possible substances rather than one single, named analyte.

Rates data updated October 2026.

How much does General-Purpose Immunoassay Lab Test cost?

$19.95

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $19.95 for this service. The price depends on where it is billed: about $15.85 from a physician practice, and about $43.65 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.85$11.22 to $19.95
FacilityA hospital or hospital-owned outpatient department$43.65$26.92 to $79.43

How much rates vary

Facilitymedian $44 · 10th to 90th $16 to $120Professionalmedian $16 · 10th to 90th $8 to $21
$5$10$20$50$100$200facility $44professional $16

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$8.91
Median
$11.22
Typical High
$23.99
Aetna
Setting
Professional
Modifier
None
Typical Low
$8.91
Median
$8.91
Typical High
$13.18
Ambetter
Setting
Professional
Modifier
None
Typical Low
$11.48
Median
$18.20
Typical High
$21.38
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$25.70
Median
$52.48
Typical High
$123.03
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$15.85
Median
$19.95
Typical High
$26.92
BCBS South Carolina
Setting
Professional
Modifier
QW · Waived lab test
Typical Low
$11.48
Median
$11.48
Typical High
$12.30
Cigna
Setting
Facility
Modifier
None
Typical Low
$21.88
Median
$34.67
Typical High
$72.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$5.89
Median
$7.94
Typical High
$14.79
Medcost
Setting
Facility
Modifier
None
Typical Low
$8.71
Median
$12.02
Typical High
$83.18
Medcost
Setting
Professional
Modifier
None
Typical Low
$12.88
Median
$19.50
Typical High
$20.89
United
Setting
Facility
Modifier
None
Typical Low
$10.47
Median
$10.47
Typical High
$13.80
United
Setting
Professional
Modifier
None
Typical Low
$4.79
Median
$8.13
Typical High
$16.22
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$4.47
Median
$4.47
Typical High
$4.57
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$1.82
Median
$1.82
Typical High
$1.82

Where South Carolina sits

The same service costs 5.2 times more in Minnesota than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 7th of 51

$19.95

MN $45.71MD $8.71

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.