go back

General-Purpose Immunoassay Lab Test

Missouri rates for HCPCS 83516

A laboratory test that uses an antibody-based method to detect and measure a specific substance in a sample, applied when there is no more specific, dedicated test already established for that particular substance. It is a general-purpose test format applied to a wide range of possible substances rather than one single, named analyte.

Rates data updated October 2026.

How much does General-Purpose Immunoassay Lab Test cost?

$13.80

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $13.80 for this service. The price depends on where it is billed: about $11.22 from a physician practice, and about $20.42 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$11.22$6.92 to $23.44
FacilityA hospital or hospital-owned outpatient department$20.42$13.80 to $31.62

How much rates vary

Facilitymedian $20 · 10th to 90th $10 to $98Professionalmedian $11 · 10th to 90th $6 to $24
$5$10$20$50$100facility $20professional $11

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$10.00
Median
$14.45
Typical High
$21.38
Aetna
Setting
Professional
Modifier
None
Typical Low
$9.77
Median
$10.00
Typical High
$13.18
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$11.48
Median
$11.48
Typical High
$53.70
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$5.75
Median
$18.62
Typical High
$28.84
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$17.38
Median
$22.91
Typical High
$43.65
Cigna
Setting
Facility
Modifier
None
Typical Low
$15.14
Median
$25.12
Typical High
$66.07
Cigna
Setting
Professional
Modifier
None
Typical Low
$6.76
Median
$13.18
Typical High
$24.55
Medica
Setting
Facility
Modifier
None
Typical Low
$10.47
Median
$20.89
Typical High
$97.72
Medica
Setting
Professional
Modifier
None
Typical Low
$5.25
Median
$8.13
Typical High
$14.45
United
Setting
Facility
Modifier
None
Typical Low
$10.47
Median
$10.47
Typical High
$10.47
United
Setting
Professional
Modifier
None
Typical Low
$4.79
Median
$8.51
Typical High
$15.49
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$4.90
Median
$5.01
Typical High
$6.61
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$1.95
Median
$2.00
Typical High
$2.63

Where Missouri sits

The same service costs 5.2 times more in Minnesota than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 16th of 51

$13.80

MN $45.71MD $8.71

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.