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Lung Cancer Outlook Signature Test

Nationwide rates for HCPCS 81538

A specialized laboratory test used in advanced lung cancer that measures a set of markers in a patient sample and combines them into a single result placing the person in a better or poorer outlook group. The result is used to help judge which type of treatment is most likely to benefit them.

Rates data updated July 2026.

Facilitymedian $4,074 · 10th–90th $2,188$11,2200%10%20%10th90th$4,074Professionalmedian $2,344 · 10th–90th $1,148$5,1290%10%20%10th90th$2,344$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$4,365.16
Typical High
$11,481.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,380.38
Median
$2,290.87
Typical High
$5,128.61
BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$3,890.45
Typical High
$12,022.64
BCBS
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$1,148.15
Typical High
$4,168.69
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$5,754.40
Typical High
$12,302.69
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$3,467.37
Typical High
$6,918.31
United
Setting
Facility
Modifier
Global
Typical Low
$1,202.26
Median
$2,884.03
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$891.25
Median
$1,698.24
Typical High
$3,890.45