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Lung Cancer Outlook Signature Test

California rates for HCPCS 81538

A specialized laboratory test used in advanced lung cancer that measures a set of markers in a patient sample and combines them into a single result placing the person in a better or poorer outlook group. The result is used to help judge which type of treatment is most likely to benefit them.

Rates data updated July 2026.

How much does Lung Cancer Outlook Signature Test cost?

$2,884

Typical negotiated rate. In California, July 2026.

Insurers have agreed to pay about $2,884 for this service. The price depends on where it is billed: about $2,239 from a physician practice, and about $6,607 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 10 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,239$1,318 to $4,074
FacilityA hospital or hospital-owned outpatient department$6,607$4,074 to $10,471

How much rates vary

Facilitymedian $6,607 · 10th to 90th $2,455 to $16,218Professionalmedian $2,239 · 10th to 90th $1,122 to $14,454
$100.0$500.0$2.0K$10.0Kfacility $6,607professional $2,239

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,630.27
Median
$6,606.93
Typical High
$17,782.79
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,380.38
Median
$2,290.87
Typical High
$19,054.61
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,348.96
Median
$7,413.10
Typical High
$14,454.40
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,148.15
Median
$1,288.25
Typical High
$5,248.07
Blue Shield
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$6,760.83
Typical High
$8,511.38
Blue Shield
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$3,981.07
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$5,128.61
Typical High
$9,772.37
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,148.15
Median
$1,905.46
Typical High
$8,709.64
Contra Costa Health
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$3,162.28
Typical High
$3,890.45
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,570.40
Median
$3,162.28
Typical High
$5,011.87
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$13,489.63
Median
$13,489.63
Typical High
$13,489.63
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$14,454.40
Median
$21,379.62
Typical High
$21,379.62
Providence
Setting
Facility
Modifier
Global
Typical Low
$1,819.70
Median
$3,467.37
Typical High
$8,511.38
Providence
Setting
Professional
Modifier
Global
Typical Low
$1,258.93
Median
$2,884.03
Typical High
$7,943.28
Sutter Health Plus
Setting
Professional
Modifier
Global
Typical Low
$10,000.00
Median
$10,000.00
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$1,905.46
Median
$2,884.03
Typical High
$3,311.31
United
Setting
Professional
Modifier
Global
Typical Low
$891.25
Median
$1,202.26
Typical High
$5,754.40

Where California sits

The same service costs 4.1 times more in Alaska than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

California $2,884 · 13th of 51
AK $6,457RI $1,585

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.