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Lung Cancer Outlook Signature Test

Illinois rates for HCPCS 81538

A specialized laboratory test used in advanced lung cancer that measures a set of markers in a patient sample and combines them into a single result placing the person in a better or poorer outlook group. The result is used to help judge which type of treatment is most likely to benefit them.

Rates data updated July 2026.

Facilitymedian $4,467 · 10th–90th $2,455$7,9430%20%10th90th$4,467Professionalmedian $2,399 · 10th–90th $1,413$5,3700%20%40%10th90th$2,399$5.0$20.0$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,344.23
Median
$4,466.84
Typical High
$5,888.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,819.70
Median
$2,344.23
Typical High
$5,370.32
BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$15,135.61
Typical High
$46,773.51
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$2,884.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$5,370.32
Median
$6,760.83
Typical High
$13,182.57
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,412.54
Median
$3,467.37
Typical High
$4,897.79
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$2,570.40
Median
$3,981.07
Typical High
$5,623.41
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$3,715.35
Median
$3,715.35
Typical High
$3,715.35
United
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$2,884.03
Typical High
$5,754.40
United
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,288.25
Typical High
$2,884.03